Laminin α1 Regulates Age-Related Mesangial Cell Proliferation and Mesangial Matrix Accumulation through the TGF-β Pathway

Laminin α1 (LAMA1), a subunit of the laminin-111 basement membrane component, has been implicated in various biological functions in vivo and in vitro. Although LAMA1 is present in kidney, its roles in the kidney are unknown because of early embryonic lethality. Herein, we used a viable conditional...

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Detalhes bibliográficos
Main Authors: Ning, Liang, Kurihara, Hidetake, de Vega, Susana, Ichikawa-Tomikawa, Naoki, Xu, Zhuo, Nonaka, Risa, Kazuno, Saiko, Yamada, Yoshihiko, Miner, Jeffrey H., Arikawa-Hirasawa, Eri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044709/
https://ncbi.nlm.nih.gov/pubmed/24720953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.02.006
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