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Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth
Laminin-1, an extracellular matrix molecule, promotes neurite outgrowth through the interaction of integrin and actin. Monosialoganglioside GM1 in the lipid rafts associates with and activates the NGF receptor TrkA, and enhances neurite outgrowth. However, the role of GM1 in laminin-1-induced neurit...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Company of Biologists
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714420/ https://ncbi.nlm.nih.gov/pubmed/19118221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.030338 |
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