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Crystal structure-based comparison of two NAMPT inhibitors
Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) is a novel strategy for cancer therapy, but only two inhibitors of NAMPT (FK866 and CHS828) have progressed into clinical trials. This study seeks to compare a novel potent NAMPT inhibitor, MS0, with a classical inhibitor FK866 in their bi...
Gorde:
| Argitaratua izan da: | Acta Pharmacol Sin |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800471/ https://ncbi.nlm.nih.gov/pubmed/28858298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.80 |
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