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Downregulation of STAT3/NF-κB potentiates gemcitabine activity in pancreatic cancer cells
There is an unmet need to develop new agents or strategies against therapy resistant pancreatic cancer (PanCA). Recent studies from our laboratory showed that STAT3 negatively regulates NF-κB and that inhibition of this crosstalk using Nexrutine(®) (Nx) reduces transcriptional activity of COX-2. Inh...
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| Publicat a: | Mol Carcinog |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800424/ https://ncbi.nlm.nih.gov/pubmed/27208550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22503 |
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