Combined targeting of Stat3/NFκB/Cox-2/EP4 for effective management of pancreatic cancer

PURPOSE: Near equal rates of incidence and mortality emphasize the need for novel targeted approaches for better management of pancreatic cancer patients. Inflammatory molecules NFκB and Stat3 are overexpressed in pancreatic tumors. Inhibition of one protein allows cancer cells to survive using the...

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Bibliografische gegevens
Hoofdauteurs: Gong, Jingjing, Xie, Jianping, Bedolla, Roble, Rivas, Paul, Chakravarthy, Divya, Freeman, James W, Reddick, Robert, Kopetz, Scott, Peterson, Amanda, Wang, Huamin, Fischer, Susan M, Kumar, Addanki P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969421/
https://ncbi.nlm.nih.gov/pubmed/24520096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1664
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