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NQO1 suppresses NF-κB-p300 interaction to regulate inflammatory mediators associated with prostate tumorigenesis

NADPH reductase NQO1 is needed to maintain a cellular pool of antioxidants and this enzyme may contribute to tumorigenesis, on the basis of studies in NQO1-deficient mice. In this work, we sought deeper insights into how NQO1 contributes to prostate carcinogenesis, a setting where oxidative stress a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thapa, Dinesh, Meng, Peng, Bedolla, Roble G., Reddick, Robert L., Kumar, Addanki P., Ghosh, Rita
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184940/
https://ncbi.nlm.nih.gov/pubmed/25125658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0562
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