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PSD-95 regulates D(1) dopamine receptor resensitization, but not receptor-mediated Gs-protein activation

The present study aims to define the role of postsynaptic density (PSD)-95 in the regulation of dopamine (DA) receptor function. We found that PSD-95 physically associates with either D(1) or D(2) DA receptors in co-transfected HEK-293 cells. Stimulation of DA receptors altered the association betwe...

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Détails bibliographiques
Publié dans:Cell Res
Auteurs principaux: Sun, Peihua, Wang, Jingru, Gu, Weihua, Cheng, Wei, Jin, Guo-zhang, Friedman, Eitan, Zheng, Jie, Zhen, Xuechu
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800406/
https://ncbi.nlm.nih.gov/pubmed/19274064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2009.30
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