Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and mitochondrial respiration

BACKGROUND: Metabolic reprogramming is shaped to support specific cell functions since cellular metabolism controls the final outcome of immune response. Multiple sclerosis (MS) is an autoimmune disease resulting from loss of immune tolerance against central nervous system (CNS) myelin. Metabolic al...

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Detaylı Bibliyografya
Yayımlandı:Metabolism
Asıl Yazarlar: La Rocca, Claudia, Carbone, Fortunata, De Rosa, Veronica, Colamatteo, Alessandra, Galgani, Mario, Perna, Francesco, Lanzillo, Roberta, Brescia Morra, Vincenzo, Orefice, Giuseppe, Cerillo, Ilaria, Florio, Ciro, Maniscalco, Giorgia Teresa, Salvetti, Marco, Centonze, Diego, Uccelli, Antonio, Longobardi, Salvatore, Visconti, Andrea, Matarese, Giuseppe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: W.B. Saunders 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800394/
https://ncbi.nlm.nih.gov/pubmed/29132538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2017.08.011
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