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Manufacturing history of etanercept (Enbrel(®)): Consistency of product quality through major process revisions
Etanercept (ETN) (Enbrel®) is a soluble protein that binds to, and specifically inhibits, tumor necrosis factor (TNF), a proinflammatory cytokine. ETN is synthesized in Chinese hamster ovary cells by recombinant DNA technology as a fusion protein, with a fully human TNFRII ectodomain linked to the F...
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| Publié dans: | MAbs |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800370/ https://ncbi.nlm.nih.gov/pubmed/29020515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1388483 |
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