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Manufacturing history of etanercept (Enbrel(®)): Consistency of product quality through major process revisions
Etanercept (ETN) (Enbrel®) is a soluble protein that binds to, and specifically inhibits, tumor necrosis factor (TNF), a proinflammatory cytokine. ETN is synthesized in Chinese hamster ovary cells by recombinant DNA technology as a fusion protein, with a fully human TNFRII ectodomain linked to the F...
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| Опубликовано в: : | MAbs |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800370/ https://ncbi.nlm.nih.gov/pubmed/29020515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1388483 |
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