Phenotypic co-receptor tropism and Maraviroc sensitivity in HIV-1 subtype C from East Africa

Genotypic tropism testing (GTT) for co-receptor usage is a recommended tool for clinical practice before administration of the CCR5-antagonist maraviroc. For some isolates, phenotypic tropism testing (PTT) revealed discordant results with GTT. In this study, we performed a comparative study between...

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Publicado en:Sci Rep
Autores principales: Siddik, Abu Bakar, Haas, Alexandra, Rahman, Md Shanawazur, Aralaguppe, Shambhu Ganeshappa, Amogne, Wondwossen, Bader, Joelle, Klimkait, Thomas, Neogi, Ujjwal
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799384/
https://ncbi.nlm.nih.gov/pubmed/29403064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20814-2
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