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Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms
While α(sk)-actin isoforms predominate in adult striated muscle, skeletal muscle-specific knockouts of non-muscle cytoplasmic β(cyto)- or γ(cyto)-actin each cause a mild, but progressive myopathy affected by an unknown mechanism. Using transmission electron microscopy, we identified morphological ab...
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| Publicat a: | FEBS J |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5799018/ https://ncbi.nlm.nih.gov/pubmed/29265728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14367 |
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