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Xanthine oxidase is hyper-active in Duchenne muscular dystrophy

Generation of superoxide by xanthine oxidase can be stimulated under ischemic and aberrant calcium homeostasis. Because patients and mice with Duchenne muscular dystrophy (DMD) suffer from ischemia and excessive calcium influx, we tested the hypothesis that xanthine oxidase activity is elevated and...

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Dades bibliogràfiques
Publicat a:Free Radic Biol Med
Autors principals: Lindsay, Angus, McCourt, Preston M., Karachunski, Peter, Lowe, Dawn A., Ervasti, James M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599518/
https://ncbi.nlm.nih.gov/pubmed/30312761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2018.10.404
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