Emerging roles of DROSHA beyond primary microRNA processing

DROSHA is the catalytic subunit of the Microprocessor complex, which initiates microRNA (miRNA) maturation in the nucleus by recognizing and cleaving hairpin precursors embedded in primary transcripts. However, accumulating evidence suggests that not all hairpin substrates of DROSHA are associated w...

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Bibliographic Details
Published in:RNA Biol
Main Authors: Lee, Dooyoung, Shin, Chanseok
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798959/
https://ncbi.nlm.nih.gov/pubmed/29171328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1405210
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