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Intronic microRNA precursors that bypass Drosha processing
MicroRNAs (miRNAs) are ~22-nucleotide endogenous RNAs that often repress the expression of complementary messenger RNAs1. In animals, miRNAs derive from characteristic hairpins in primary transcripts through two sequential RNase III-mediated cleavages; Drosha cleaves near the base of the stem to lib...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475599/ https://ncbi.nlm.nih.gov/pubmed/17589500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05983 |
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