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Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
A critical step during human microRNA maturation is the processing of the primary microRNA transcript by the nuclear RNaseIII enzyme Drosha to generate the ∼60-nucleotide precursor microRNA hairpin. How Drosha recognizes primary RNA substrates and selects its cleavage sites has remained a mystery, e...
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| Publicado no: | EMBO J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15565168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600491 |
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