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Processing of intronic microRNAs
The majority of human microRNA (miRNA) loci are located within intronic regions and are transcribed by RNA polymerase II as part of their hosting transcription units. The primary transcripts are cleaved by Drosha to release ∼70 nt pre-miRNAs that are subsequently processed by Dicer to generate matur...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1794378/ https://ncbi.nlm.nih.gov/pubmed/17255951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601512 |
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