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Processing of intronic microRNAs

The majority of human microRNA (miRNA) loci are located within intronic regions and are transcribed by RNA polymerase II as part of their hosting transcription units. The primary transcripts are cleaved by Drosha to release ∼70 nt pre-miRNAs that are subsequently processed by Dicer to generate matur...

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Detalles Bibliográficos
Main Authors: Kim, Young-Kook, Kim, V Narry
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794378/
https://ncbi.nlm.nih.gov/pubmed/17255951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601512
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