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Processing of intronic microRNAs

The majority of human microRNA (miRNA) loci are located within intronic regions and are transcribed by RNA polymerase II as part of their hosting transcription units. The primary transcripts are cleaved by Drosha to release ∼70 nt pre-miRNAs that are subsequently processed by Dicer to generate matur...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kim, Young-Kook, Kim, V Narry
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794378/
https://ncbi.nlm.nih.gov/pubmed/17255951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601512
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