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Role of MLH1 methylation in esophageal cancer carcinogenesis and its clinical significance

The mutL homolog-1 (MLH1) is a DNA mismatch repair gene and has been reported to be frequently methylated in numerous cancers. However, the association between MLH1 methylation and esophageal cancer (EC), as well as its clinical significance, remains unclear. Hence, we conducted a systematic meta-an...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Li, Jinyun, Ye, Dong, Wang, Lei, Peng, Yingying, Li, Qun, Deng, Hongxia, Zhou, Chongchang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798571/
https://ncbi.nlm.nih.gov/pubmed/29440913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S154999
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