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Role of MLH1 methylation in esophageal cancer carcinogenesis and its clinical significance

The mutL homolog-1 (MLH1) is a DNA mismatch repair gene and has been reported to be frequently methylated in numerous cancers. However, the association between MLH1 methylation and esophageal cancer (EC), as well as its clinical significance, remains unclear. Hence, we conducted a systematic meta-an...

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Bibliografske podrobnosti
izdano v:Onco Targets Ther
Main Authors: Li, Jinyun, Ye, Dong, Wang, Lei, Peng, Yingying, Li, Qun, Deng, Hongxia, Zhou, Chongchang
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798571/
https://ncbi.nlm.nih.gov/pubmed/29440913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S154999
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