Role of MLH1 methylation in esophageal cancer carcinogenesis and its clinical significance

The mutL homolog-1 (MLH1) is a DNA mismatch repair gene and has been reported to be frequently methylated in numerous cancers. However, the association between MLH1 methylation and esophageal cancer (EC), as well as its clinical significance, remains unclear. Hence, we conducted a systematic meta-an...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Li, Jinyun, Ye, Dong, Wang, Lei, Peng, Yingying, Li, Qun, Deng, Hongxia, Zhou, Chongchang
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798571/
https://ncbi.nlm.nih.gov/pubmed/29440913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S154999
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