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Toward Personalised Liquid Biopsies for Urothelial Carcinoma: Characterisation of ddPCR and Urinary cfDNA for the Detection of the TERT 228 G>A/T Mutation
BACKGROUND: TERT promotor mutations are present in >75% of bladder tumours; these mutations are also detectable in urine. Previous studies have used urinary pellet DNA, and semi-quantitative methods unsuitable for detecting very low mutant allele frequencies. OBJECTIVE: In this proof-of-principle...
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| Pubblicato in: | Bladder Cancer |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
IOS Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798520/ https://ncbi.nlm.nih.gov/pubmed/29430506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/BLC-170152 |
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