Molecular Correlates of In Vitro Responses to Dacomitinib and Afatinib in Bladder Cancer

BACKGROUND: The HER family of proteins (EGFR, HER2, HER3 and HER4) have long been thought to be therapeutic targets for bladder cancer, but previous clinical trials targeting these proteins have been disappointing. Second generation agents may be more effective. OBJECTIVE: The aim of this study was...

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Veröffentlicht in:Bladder Cancer
Hauptverfasser: Tamura, Shuzo, Wang, Yin, Veeneman, Brendan, Hovelson, Daniel, Bankhead, Armand, Broses, Luke J., Lorenzatti Hiles, Guadalupe, Liebert, Monica, Rubin, John R., Day, Kathleen C., Hussain, Maha, Neamati, Nouri, Tomlins, Scott, Palmbos, Philip L., Grivas, Petros, Day, Mark L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2018
Schlagworte:
Research Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798519/
https://ncbi.nlm.nih.gov/pubmed/29430509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/BLC-170144
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