Molecular Correlates of In Vitro Responses to Dacomitinib and Afatinib in Bladder Cancer

BACKGROUND: The HER family of proteins (EGFR, HER2, HER3 and HER4) have long been thought to be therapeutic targets for bladder cancer, but previous clinical trials targeting these proteins have been disappointing. Second generation agents may be more effective. OBJECTIVE: The aim of this study was...

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Bibliographic Details
Published in:Bladder Cancer
Main Authors: Tamura, Shuzo, Wang, Yin, Veeneman, Brendan, Hovelson, Daniel, Bankhead, Armand, Broses, Luke J., Lorenzatti Hiles, Guadalupe, Liebert, Monica, Rubin, John R., Day, Kathleen C., Hussain, Maha, Neamati, Nouri, Tomlins, Scott, Palmbos, Philip L., Grivas, Petros, Day, Mark L.
Format: Artigo
Language:Inglês
Published: IOS Press 2018
Subjects:
Research Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798519/
https://ncbi.nlm.nih.gov/pubmed/29430509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/BLC-170144
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