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Pyrimidine nucleotides containing a (S)-methanocarba ring as P2Y(6) receptor agonists
Both agonists and antagonists of the UDP-activated P2Y(6) receptor (P2Y(6)R) have been proposed for therapeutic use, in conditions such as cancer, inflammation, neurodegeneration and diabetes. Uracil nucleotides containing a south-bicyclo[3.1.0]hexane ((S)-methanocarba) ring system in place of the r...
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| Izdano u: | Medchemcomm |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Royal Society of Chemistry
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798474/ https://ncbi.nlm.nih.gov/pubmed/29423136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00397h |
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