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Strongly enhanced bacterial bioluminescence with the ilux operon for single-cell imaging

Bioluminescence imaging of single cells is often complicated by the requirement of exogenous luciferins that can be poorly cell-permeable or produce high background signal. Bacterial bioluminescence is unique in that it uses reduced flavin mononucleotide as a luciferin, which is abundant in all cell...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gregor, Carola, Gwosch, Klaus C., Sahl, Steffen J., Hell, Stefan W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798359/
https://ncbi.nlm.nih.gov/pubmed/29339494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715946115
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