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Tumor suppressor APC is an attenuator of spindle-pulling forces during C. elegans asymmetric cell division
The adenomatous polyposis coli (APC) tumor suppressor has dual functions in Wnt/β-catenin signaling and accurate chromosome segregation and is frequently mutated in colorectal cancers. Although APC contributes to proper cell division, the underlying mechanisms remain poorly understood. Here we show...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798331/ https://ncbi.nlm.nih.gov/pubmed/29348204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712052115 |
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