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CaMKII regulates the depalmitoylation and synaptic removal of the scaffold protein AKAP79/150 to mediate structural long-term depression
Both long-term potentiation (LTP) and depression (LTD) of excitatory synapse strength require the Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) and its autonomous activity generated by Thr-286 autophosphorylation. Additionally, LTP and LTD are correlated with dendritic spine enlargeme...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798287/ https://ncbi.nlm.nih.gov/pubmed/29196604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813808 |
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