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Covariate Selection for Association Screening in Multi-Phenotype Genetic studies

Testing for associations in big data faces the problem of multiple comparisons, with true signals difficult to detect on the background of all associations queried. This is particularly true in human genetic association studies where phenotypic variation is often driven by numerous variants of small...

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書目詳細資料
發表在:Nat Genet
Main Authors: Aschard, Hugues, Guillemot, Vincent, Vilhjalmsson, Bjarni, Patel, Chirag J, Skurnik, David, Ye, Jimmy, Wolpin, Brian, Kraft, Peter, Zaitlen, Noah
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797835/
https://ncbi.nlm.nih.gov/pubmed/29038595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3975
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