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Variation in predictive ability of common genetic variants by established strata - The example of breast cancer and age
BACKGROUND: Recent studies of breast cancer and common genetic markers have failed to identify pervasive gene-gene and gene-environment interactions. Theoretical considerations also suggest that the contribution of modest interactions to risk discrimination in the general population is likely small....
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| Publicado en: | Epidemiology |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5082110/ https://ncbi.nlm.nih.gov/pubmed/25380502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0000000000000195 |
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