Performance of Common Genetic Variants in Breast-Cancer Risk Models

BACKGROUND: Genomewide association studies have identified multiple genetic variants associated with breast cancer. The extent to which these variants add to existing risk-assessment models is unknown. METHODS: We used information on traditional risk factors and 10 common genetic variants associated...

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Main Authors: Wacholder, Sholom, Hartge, Patricia, Prentice, Ross, Garcia-Closas, Montserrat, Feigelson, Heather Spencer, Diver, W. Ryan, Thun, Michael J., Cox, David G., Hankinson, Susan E., Kraft, Peter, Rosner, Bernard, Berg, Christine D., Brinton, Louise A., Lissowska, Jolanta, Sherman, Mark E., Chlebowski, Rowan, Kooperberg, Charles, Jackson, Rebecca D., Buckman, Dennis W., Hui, Peter, Pfeiffer, Ruth, Jacobs, Kevin B., Thomas, Gilles D., Hoover, Robert N., Gail, Mitchell H., Chanock, Stephen J., Hunter, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921181/
https://ncbi.nlm.nih.gov/pubmed/20237344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0907727
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