The Contributions of Breast Density and Common Genetic Variation to Breast Cancer Risk

We evaluated whether a 76-locus polygenic risk score (PRS) and Breast Imaging Reporting and Data System (BI-RADS) breast density were independent risk factors within three studies (1643 case patients, 2397 control patients) using logistic regression models. We incorporated the PRS odds ratio (OR) in...

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Bibliografiske detaljer
Udgivet i:J Natl Cancer Inst
Main Authors: Vachon, Celine M., Pankratz, V. Shane, Scott, Christopher G., Haeberle, Lothar, Ziv, Elad, Jensen, Matthew R., Brandt, Kathleen R., Whaley, Dana H., Olson, Janet E., Heusinger, Katharina, Hack, Carolin C., Jud, Sebastian M., Beckmann, Matthias W., Schulz-Wendtland, Ruediger, Tice, Jeffrey A., Norman, Aaron D., Cunningham, Julie M., Purrington, Kristen S., Easton, Douglas F., Sellers, Thomas A., Kerlikowske, Karla, Fasching, Peter A., Couch, Fergus J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Brief Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598340/
https://ncbi.nlm.nih.gov/pubmed/25745020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju397
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