The Contributions of Breast Density and Common Genetic Variation to Breast Cancer Risk

We evaluated whether a 76-locus polygenic risk score (PRS) and Breast Imaging Reporting and Data System (BI-RADS) breast density were independent risk factors within three studies (1643 case patients, 2397 control patients) using logistic regression models. We incorporated the PRS odds ratio (OR) in...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Vachon, Celine M., Pankratz, V. Shane, Scott, Christopher G., Haeberle, Lothar, Ziv, Elad, Jensen, Matthew R., Brandt, Kathleen R., Whaley, Dana H., Olson, Janet E., Heusinger, Katharina, Hack, Carolin C., Jud, Sebastian M., Beckmann, Matthias W., Schulz-Wendtland, Ruediger, Tice, Jeffrey A., Norman, Aaron D., Cunningham, Julie M., Purrington, Kristen S., Easton, Douglas F., Sellers, Thomas A., Kerlikowske, Karla, Fasching, Peter A., Couch, Fergus J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598340/
https://ncbi.nlm.nih.gov/pubmed/25745020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju397
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