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Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
The so-called amyloid hypothesis, that the accumulation and deposition of oligomeric or fibrillar amyloid β (Aβ) peptide is the primary cause of Alzheimer's disease (AD), has been the mainstream concept underlying AD research for over 20 years. However, all attempts to develop Aβ-targeting drug...
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| Publicado no: | Front Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5797629/ https://ncbi.nlm.nih.gov/pubmed/29440986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00025 |
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