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Is the Amyloid Hypothesis of Alzheimer's disease therapeutically relevant?
The conventional view of AD (Alzheimer's disease) is that much of the pathology is driven by an increased load of β-amyloid in the brain of AD patients (the ‘Amyloid Hypothesis’). Yet, many therapeutic strategies based on lowering β-amyloid have so far failed in clinical trials. This failure of...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686157/ https://ncbi.nlm.nih.gov/pubmed/22891628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120653 |
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