α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise

The loss of protein homeostasis that has been associated with aging leads to altered levels and conformational instability of proteins, which tend to form toxic aggregates. In particular, brain aging presents characteristic patterns of misfolded oligomers, primarily constituted of β-amyloid (Aβ), ta...

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Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Daniele, Simona, Pietrobono, Deborah, Fusi, Jonathan, Lo Gerfo, Annalisa, Cerri, Eugenio, Chico, Lucia, Iofrida, Caterina, Petrozzi, Lucia, Baldacci, Filippo, Giacomelli, Chiara, Galetta, Fabio, Siciliano, Gabriele, Bonuccelli, Ubaldo, Trincavelli, Maria L., Franzoni, Ferdinando, Martini, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797553/
https://ncbi.nlm.nih.gov/pubmed/29441013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00017
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