α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson’s Disease Patients and Correlate with Disease Severity

Neurodegenerative disorders (NDs) are characterized by abnormal accumulation/misfolding of specific proteins, primarily α-synuclein (α-syn), β-amyloid(1–42) (Aβ(1–42)) and tau, in both brain and peripheral tissues. In addition to oligomers, the role of the interactions of α-syn with Aβ or tau has gr...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Daniele, Simona, Frosini, Daniela, Pietrobono, Deborah, Petrozzi, Lucia, Lo Gerfo, Annalisa, Baldacci, Filippo, Fusi, Jonathan, Giacomelli, Chiara, Siciliano, Gabriele, Trincavelli, Maria Letizia, Franzoni, Ferdinando, Ceravolo, Roberto, Martini, Claudia, Bonuccelli, Ubaldo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827358/
https://ncbi.nlm.nih.gov/pubmed/29520218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00053
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