載入...

Functional loss of p53 cooperates with the in vivo microenvironment to promote malignant progression of gastric cancers

p53 mutations are frequently detected in malignant gastric cancers. However, the molecular mechanisms by which loss of p53 function promotes gastric cancer are not clear. We utilized Gan mice (K19-Wnt1/C2mE), which have functional p53 and develop intestinal-type gastric tumors, to investigate the ro...

全面介紹

Na minha lista:
書目詳細資料
發表在:Sci Rep
Main Authors: Ohtsuka, Junko, Oshima, Hiroko, Ezawa, Issei, Abe, Ryo, Oshima, Masanobu, Ohki, Rieko
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797237/
https://ncbi.nlm.nih.gov/pubmed/29396430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20572-1
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!