The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance

Ciliopathies are human disorders caused by dysfunction of primary cilia, ubiquitous microtubule-based organelles involved in signal transduction. Cilia are anchored inside the cell through basal bodies (BBs), modified centrioles also acting as microtubule-organization centers. Photoreceptors (PRs) a...

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Published in:Sci Rep
Main Authors: Ojeda Naharros, Irene, Cristian, Flavia B., Zang, Jingjing, Gesemann, Matthias, Ingham, Philip W., Neuhauss, Stephan C. F., Bachmann-Gagescu, Ruxandra
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797153/
https://ncbi.nlm.nih.gov/pubmed/29396404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20489-9
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