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Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors

Ciliopathies are human disorders caused by dysfunction of primary cilia, ubiquitous organelles involved in transduction of environmental signals such as light sensation in photoreceptors. Concentration of signal detection proteins such as opsins in the ciliary membrane is achieved by RabGTPase-regul...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Ojeda Naharros, Irene, Gesemann, Matthias, Mateos, José M., Barmettler, Gery, Forbes, Austin, Ziegler, Urs, Neuhauss, Stephan C. F., Bachmann-Gagescu, Ruxandra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760100/
https://ncbi.nlm.nih.gov/pubmed/29281629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007150
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