Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin

OBJECTIVE: Long-term use of doxorubicin (Dox) can cause neurobiological side effects associated with depression, but the underlying mechanisms remain equivocal. While recent evidence has indicated that Neuregulin-1 (NRG1) and its ErbB receptors play an essential role in neural function, much is stil...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Liao, Dehua, Guo, Yujin, Xiang, Daxiong, Dang, Ruili, Xu, Pengfei, Cai, Hualin, Cao, Lizhi, Jiang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796460/
https://ncbi.nlm.nih.gov/pubmed/29430172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S151511
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