Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes

Doxorubicin (DOX) is a broad-spectrum antitumor drug while its use is limited due to its neurobiological side effects associated with depression. We investigated the neuroprotective efficacy of dl-3-n-butylphthalide (dl-NBP) against DOX-induced anxiety- and depression-like behaviors in rats. dl-NBP...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Liao, Dehua, Xiang, Daxiong, Dang, Ruili, Xu, Pengfei, Wang, Jiemin, Han, Wenxiu, Fu, Yingzhou, Yao, Dunwu, Cao, Lizhi, Jiang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116408/
https://ncbi.nlm.nih.gov/pubmed/30186550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9125601
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