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BRAF and MEK Inhibitors Influence the Function of Reprogrammed T Cells: Consequences for Adoptive T-Cell Therapy
BRAF and MEK inhibitors (BRAFi/MEKi), the standard treatment for patients with BRAF(V600) mutated melanoma, are currently explored in combination with various immunotherapies, notably checkpoint inhibitors and adoptive transfer of receptor-transfected T cells. Since two BRAFi/MEKi combinations with...
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| Publicado en: | Int J Mol Sci |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5796234/ https://ncbi.nlm.nih.gov/pubmed/29346301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010289 |
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