Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination

BACKGROUND: Merkel cell carcinoma (MCC) is a rare but very aggressive skin tumor that develops after integration of a truncated form of the large T-antigen (truncLT) of the Merkel cell polyomavirus (MCV) into the host’s genome. Therapeutic vaccination with dendritic cells (DCs) loaded with tumor ant...

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Detalhes bibliográficos
Publicado no:Ther Adv Med Oncol
Main Authors: Gerer, Kerstin F., Erdmann, Michael, Hadrup, Sine R., Lyngaa, Rikke, Martin, Lena-Marie, Voll, Reinhard E., Schuler-Thurner, Beatrice, Schuler, Gerold, Schaft, Niels, Hoyer, Stefanie, Dörrie, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502952/
https://ncbi.nlm.nih.gov/pubmed/28717398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834017712630
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