T-cell responses to oncogenic Merkel cell polyomavirus proteins distinguish Merkel cell carcinoma patients from healthy donors

PURPOSE: Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with strong evidence of viral carcinogenesis. The association of MCC with the Merkel cell polyomavirus (MCPyV) may explain the explicit immunogenicity of MCC. Indeed, MCPyV-encoded proteins are likely targets for cytotoxic immun...

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Main Authors: Lyngaa, Rikke, Pedersen, Natasja Wulff, Schrama, David, Thrue, Charlotte Albæk, Ibrani, Dafina, Met, Özcan, Straten, Per thor, Nghiem, Paul, Becker, Jürgen C., Hadrup, Sine Reker
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994405/
https://ncbi.nlm.nih.gov/pubmed/24526738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2697
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