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Computational Insights into the Interactions between Calmodulin and the c/nSH2 Domains of p85α Regulatory Subunit of PI3Kα: Implication for PI3Kα Activation by Calmodulin

Calmodulin (CaM) and phosphatidylinositide-3 kinase (PI3Kα) are well known for their multiple roles in a series of intracellular signaling pathways and in the progression of several human cancers. Crosstalk between CaM and PI3Kα has been an area of intensive research. Recent experiments have shown t...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ni, Duan, Liu, Dingyu, Zhang, Jian, Lu, Shaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796100/
https://ncbi.nlm.nih.gov/pubmed/29300353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010151
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