IL-10 in the microenvironment of HNSCC inhibits the CpG ODN-induced IFN-α secretion of pDCs

It has been shown that head and neck squamous cell carcinoma (HNSCC) is infiltrated by plasmacytoid dendritic cells (pDCs). The HNSCC TH2 biased microenvironment leads to strong alterations of the cellular functions of pDC and thus impairs the initiation and function of adequate immune responses. In...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncol Lett
Main Authors: Bruchhage, Karl-Ludwig, Heinrichs, Sabrina, Wollenberg, Barbara, Pries, Ralph
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795883/
https://ncbi.nlm.nih.gov/pubmed/29456743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.7772
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