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IL-10 in the microenvironment of HNSCC inhibits the CpG ODN-induced IFN-α secretion of pDCs

It has been shown that head and neck squamous cell carcinoma (HNSCC) is infiltrated by plasmacytoid dendritic cells (pDCs). The HNSCC TH2 biased microenvironment leads to strong alterations of the cellular functions of pDC and thus impairs the initiation and function of adequate immune responses. In...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Bruchhage, Karl-Ludwig, Heinrichs, Sabrina, Wollenberg, Barbara, Pries, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795883/
https://ncbi.nlm.nih.gov/pubmed/29456743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.7772
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