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IL-10 in the microenvironment of HNSCC inhibits the CpG ODN-induced IFN-α secretion of pDCs

It has been shown that head and neck squamous cell carcinoma (HNSCC) is infiltrated by plasmacytoid dendritic cells (pDCs). The HNSCC TH2 biased microenvironment leads to strong alterations of the cellular functions of pDC and thus impairs the initiation and function of adequate immune responses. In...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncol Lett
Päätekijät: Bruchhage, Karl-Ludwig, Heinrichs, Sabrina, Wollenberg, Barbara, Pries, Ralph
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795883/
https://ncbi.nlm.nih.gov/pubmed/29456743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.7772
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