The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated B(act) complex

The precise function of the trimeric retention and splicing (RES) complex in pre-mRNA splicing remains unclear. Here we dissected the role of RES during the assembly and activation of yeast spliceosomes. The efficiency of pre-mRNA splicing was significantly lower in the absence of the RES protein Sn...

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Vydáno v:Genes Dev
Hlavní autoři: Bao, Penghui, Will, Cindy L., Urlaub, Henning, Boon, Kum-Loong, Lührmann, Reinhard
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795787/
https://ncbi.nlm.nih.gov/pubmed/29330354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.308163.117
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