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Link between the causative genes of holoprosencephaly: Zic2 directly regulates Tgif1 expression

One of the causal genes for holoprosencephaly (HPE) is ZIC2 (HPE5). It belongs to the zinc finger protein of the cerebellum (Zic) family of genes that share a C2H2-type zinc finger domain, similar to the GLI family of genes. In order to clarify the role of Zic2 in gene regulation, we searched for it...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Ishiguro, Akira, Hatayama, Minoru, Otsuka, Maky I., Aruga, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794963/
https://ncbi.nlm.nih.gov/pubmed/29391420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20242-2
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