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Link between the causative genes of holoprosencephaly: Zic2 directly regulates Tgif1 expression

One of the causal genes for holoprosencephaly (HPE) is ZIC2 (HPE5). It belongs to the zinc finger protein of the cerebellum (Zic) family of genes that share a C2H2-type zinc finger domain, similar to the GLI family of genes. In order to clarify the role of Zic2 in gene regulation, we searched for it...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ishiguro, Akira, Hatayama, Minoru, Otsuka, Maky I., Aruga, Jun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794963/
https://ncbi.nlm.nih.gov/pubmed/29391420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20242-2
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